发明名称 |
METHOD FOR PREPARING MALONATE METHYLIDENE NANOPARTICLES, NANOPARTICLES OPTIONALLY CONTAINING ONE OR SEVERAL BIOLOGICALLY ACTIVE MOLECULES |
摘要 |
The invention concerns a method for preparing nanoparticles formed of a statistic polymer of at least one compound of formula (I) in which A represents a group (a) or a group (b); R1 and R2, identical or different, represent a C1-C6 alkyl group linear or branched; n = 1, 2, 3, 4, or 5, characterised in that the monomer is previously made soluble in an organic aprotic solvent miscible in water forming with the polymerisation medium a mixture non-solvent of the formed polymer. The invention also concerns said nanoparticles, containing optionally one or several biologically active molecules, and the pharmaceutical compositions containing them.
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申请公布号 |
CA2269783(A1) |
申请公布日期 |
1998.05.07 |
申请号 |
CA19972269783 |
申请日期 |
1997.10.24 |
申请人 |
VIRSOL |
发明人 |
ROQUES-CARMES, CLAUDE;COUVREUR, PATRICK;RIESS, GERARD;BRETON, PASCAL;BRU-MAGNIEZ, NICOLE;LESCURE, FRANCOIS;GUILLON, XAVIER |
分类号 |
A61K9/51;A61K31/4168;A61K31/496;A61K31/513;A61K31/7072;A61K38/00;A61K47/32;A61K47/48;C08F2/00;C08F2/08;C08F22/10;C08F22/14;C08F22/20;(IPC1-7):A61K9/51 |
主分类号 |
A61K9/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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