| 摘要 |
The present invention provides a novel human phosphoprotein (hPSHP) and polynucleotides which identify and encode hPSHP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding hPSHP. The invention also provides pharmaceutical compositions containing hPSHP or agonists and antagonists to hPSHP, and in the use of these compositions for the treatment of diseases associated with hPSHP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding hPSHP for the treatment of diseases associated with the expression of hPSHP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding hPSHP or anti hPSHP antibodies which specifically bind to hPSHP.
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