MIRROR-SYMMETRICAL SELECTION AND EVOLUTION OF NUCLEIC ACIDS
摘要
A method is disclosed for identifying and producing L-nucleic acids which interact with a target molecule having a natural configuration, as well as the L-nucleic acids produced by this method. Also disclosed is the use of D-nucleic acids which bind to the optical antipode of the target molecule as a matrix for producing L-nucleic acids with an identical sequence, and pharmaceutical compositions and kits which contain the disclosed L-nucleic acids.
申请公布号
WO9808856(A3)
申请公布日期
1998.05.07
申请号
WO1997EP04726
申请日期
1997.08.29
申请人
FUERSTE, JENS, PETER;BALD, ROLF;ERDMANN, VOLKER, A.
发明人
FUERSTE, JENS, PETER;BALD, ROLF;ERDMANN, VOLKER, A.