发明名称 |
Polyethylene-protein conjugates |
摘要 |
The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein which forms this conjugate.
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申请公布号 |
US5747646(A) |
申请公布日期 |
1998.05.05 |
申请号 |
US19950457058 |
申请日期 |
1995.06.01 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
HAKIMI, JOHN;KILIAN, PATRICIA;ROSEN, PERRY |
分类号 |
A61K38/00;A61K;A61K31/745;A61K38/16;A61K38/19;A61K38/20;A61K38/21;A61K39/00;A61K39/38;A61K39/385;A61K47/42;A61K47/48;A61P37/00;A61P37/02;A61P43/00;C07C267/00;C07C331/18;C07C331/20;C07D211/04;C07D213/63;C07D213/64;C07D213/643;C07D213/70;C07D213/83;C07D213/89;C07K;C07K1/00;C07K14/47;C07K14/52;C07K14/54;C07K14/545;C07K14/55;C07K14/555;C07K14/56;C07K14/765;C07K17/00;C07K17/02;C07K17/06;C07K17/08;C07K17/10;C08F116/02;C08F216/00;C08G65/02;C08G65/08;C08G65/26;C08G65/28;C08G65/32;C08G65/34;C08G65/48;C08H1/00;C08L23/36;C08L71/02;C12N9/96;(IPC1-7):C07K1/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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