发明名称 |
Platelet secretory transport protein |
摘要 |
Disclosed is a novel protein designated platelet secretory transport protein (PSTP). PSTP occurs in platelets and binds to syntaxin. An isolated DNA encoding PSTP, vectors and cells containing the DNA, and PSTP specific antibodies are also disclosed. A PSTP antibody can be used to target a compound to an activated platelet in a mammal for diagnostic or therapeutic purposes. Also disclosed is an in vitro screening method for identifying a compound that inhibits PSTP-syntaxin binding, and an in vitro method for identifying a compound that inhibits PSTP gene expression. |
申请公布号 |
AU4810497(A) |
申请公布日期 |
1998.05.05 |
申请号 |
AU19970048104 |
申请日期 |
1997.10.07 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
GUY L. REED |
分类号 |
G01N33/50;A61K38/00;A61K39/395;A61K45/00;A61P7/02;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;G01N33/15;G01N33/53 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|