发明名称 |
Vaccine adjuvant comprising interleukin-15 |
摘要 |
Methods of enhancing a mammal's immune response to a vaccine antigen are disclosed. Interleukin-15 can be used as a vaccine adjuvant to enhance or potentiate the immune response to a vaccine. Compositions comprising an immunogenic amount of vaccine antigen and an immunogenicity-augmenting amount of IL-15 are also provided by the invention. IL-15 can be used alone in the invention or in concurrent or sequential combination with additional vaccine adjuvants.
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申请公布号 |
US5747024(A) |
申请公布日期 |
1998.05.05 |
申请号 |
US19950504042 |
申请日期 |
1995.07.19 |
申请人 |
IMMUNEX CORPORATION |
发明人 |
GRABSTEIN, KENNETH H.;WIDMER, MICHAEL B. |
分类号 |
A61K38/20;A61K39/395;C07K14/54;C07K14/725;C07K16/24;C12N5/12;C12N15/24;(IPC1-7):A61K38/20 |
主分类号 |
A61K38/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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