Triazole and imidazole compounds and their use as antifungal therapeutic agents.

摘要

The present invention provides an azole compound represented by the formula (I): , wherein Ar is an optionally-substituted phenyl group; R<1> and R<2> are, the same or different, a hydrogen atom or a lower alkyl group, or R<1> and R<2> may combine together to form a lower alkylene group; R<3> is a hydrogen atom or an acyl group; Y is a nitrogen atom or a methine group; and A is an optionally-substituted saturated cyclic amide group bonded through a first nitrogen atom, or a salt thereof, which is useful for prevention and therapy of fungal infections of mammals as antifungal agent.