发明名称 HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS
摘要 The present invention is directed to compound of formula (I), wherein R1, R2, R3, R4, R5, X, Y and (Ia) are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.
申请公布号 WO9817643(A1) 申请公布日期 1998.04.30
申请号 WO1997US17809 申请日期 1997.10.06
申请人 AGOURON PHARMACEUTICALS, INC.;SYNTEX (U.S.A.) INC. 发明人 BENDER, STEVEN, L.;CASTELHANO, ARLINDO, L.;CHONG, WESLEY, K., M.;ABREO, MELWYN, A.;BILLEDEAU, ROLAND, J.;CHEN, JIAN, JEFFREY;DEAL, JUDITH, G.
分类号 C07D233/58;A61K31/00;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/407;A61K31/415;A61K31/4164;A61K31/4178;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/55;A61K38/00;A61P1/00;A61P1/02;A61P9/00;A61P9/10;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P43/00;C07D207/32;C07D207/327;C07D207/337;C07D231/12;C07D233/54;C07D233/56;C07D307/54;C07D333/24;C07D333/26;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D403/12;C07D405/10;C07D405/12;C07D405/14;C07D409/12;C07D487/04;C07D487/08;C07D498/08;C07D521/00;C07K5/072;(IPC1-7):C07D207/327;C07K5/078;A61K38/05;C07D401/00;C07D403/00;C07D405/00;C07D409/00 主分类号 C07D233/58
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