发明名称 |
PERMEATION ENHANCERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS, DEVICES, AND METHODS |
摘要 |
The present invention is directed to the transdermal administration of at least one drug together with a suitable amount of a permeation enhancer comprising monoalkyl ethers of polyethyleneglycol and their alkyl or aryl carboxylic acid esters and carboxymethyl ethers. The invention includes a transdermal drug delivery device comprising a matrix adapted to be placed in drug-and-permeation enhancer-transmitting relation with a skin site. The matrix contains sufficient amounts of the permeation enhancer and drug, in combination, to continuously administer drug to the systemic circulation of a patient at a therapeutically effective rate. The invention is also directed to compositions and methods for transdermal administration of at least one drug together with a permeation enhancer of this invention, alone or in combination with other enhancers.
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申请公布号 |
CA2264687(A1) |
申请公布日期 |
1998.04.30 |
申请号 |
CA19972264687 |
申请日期 |
1997.10.23 |
申请人 |
ALZA CORPORATION |
发明人 |
LEE, EUN SOO;YUM, SU IL |
分类号 |
A61K9/00;A61K9/70;A61K31/216;A61K31/4045;A61K31/407;A61K31/5517;A61K31/565;A61K31/568;A61K47/10;A61K47/12;A61K47/14;(IPC1-7):A61K9/70 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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