| 摘要 |
<p>Bovine bone cells express osteometrin, a 35 kDA phosphoprotein specifically expressed in bone and dentin tissue. We have found that protein reactive with anti-osteometrin antisera is detectable in a wide range of species, and that osteometrin expression is detectable during mineralization of bone tissue. Our findings establish that osteometrin is an indicator of bone metabolism and may be involved in highly conserved aspects of bone and dentin metabolism. Osteometrin is used as a marker for osteoporosis and bone cancer.</p> |
