发明名称 FRAGMENTS D'ANTICORPS A CHAINE UNIQUE ANTI-P53 ET UTILISATION
摘要 The invention concerns single-chain antibodies directed against the p53 protein, capable of being expressed in tumoral cells, capable of restoring a DNA binding in vitro and a transcription activator function in vivo. The invention also concerns nucleic acids coding for these molecules, the vectors containing them and their uses.
申请公布号 FR2755144(A1) 申请公布日期 1998.04.30
申请号 FR19960013176 申请日期 1996.10.29
申请人 RHONE POULENC RORER SA 发明人 LESPAGNOL MICHEL;DEBUSSCHE LAURENT
分类号 C12N15/09;A61K31/711;A61K35/00;A61K38/00;A61K39/395;A61K48/00;C07K14/47;C07K16/18;C12P21/08;(IPC1-7):C12P21/02;C12N15/13 主分类号 C12N15/09
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