发明名称 SUBSTITUTED AMINOALKANEPHOSPHONIC ACIDS
摘要 Compounds have the formula (I), in which R1 stands for hydroxy or an aliphatic, araliphatic or aromatic radical; X stands for a bivalent aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic, heteroarylaliphatic or aromatic radical; R2 stands for hydrogen or an aliphatic or araliphatic radical; alk stands for lower alkylidene; and R3, R4 and R5 independently represent hydrogen, lower alkyl, halogen, trifluoromethyl, cyano or nitro. These compounds and their salts may be used for treating pathological conditions which respond to the blocking of exciter amino acid receptors, and for producing pharmaceutical compositions.
申请公布号 CA2269807(A1) 申请公布日期 1998.04.30
申请号 CA19972269807 申请日期 1997.10.22
申请人 NOVARTIS AG 发明人 ACKLIN, PIERRE;OFNER, SILVIO;AUBERSON, YVES;VEENSTRA, SIEM JACOB;ALLGEIER, HANS
分类号 A61K31/675;A61P9/00;A61P25/00;A61P25/08;A61P43/00;C07F9/6509;(IPC1-7):C07F9/650 主分类号 A61K31/675
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