| 摘要 |
<p>A silver implantable medical device (29) includes a structure (12) adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one layer (18) of a bioactive material deposited on one surface of structure (12); and at least one porous layer (20) deposited over the bioactive material layer (18) deposited on one surface of structure (12) and the bioactive-material-free surface. Also included is a layer or impregnation of silver (45). Preferably, the structure (12) is a coronary stent. The porous layer (20) is comprised of a polymer applied preferably by vapor or plasma deposition and provides a controlled release of the bioactive material. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative, which is deposited without solvents, heat or catalysts, merely by condensation of a monomer vapor. Silver is included as a base material, coating or included in a carrier, drug, medicament material utilized with the implantable stent.</p> |
