| 摘要 |
A continuous fermenter vessel (1) such as an air-lift fermenter for receiving a suspension culture of cells, the vessel comprising; means (19), in use, for agitating a suspension culture received in the vessel and causing a gross flow movement of the suspension culture, an inlet for continuously supplying culture medium to the vessel, an outlet for removing culture supernatant (21), and a filter material (5, 7) between the outlet and the vessel (23) to prevent removal of cells from the suspension culture (21) wherein the filter material (5, 7) is located such that, in use, the gross flow movement of the suspension culture substantially prevents clogging of the filter material by cells and/or cell debris. |
