发明名称 Method of making vitamin K1
摘要 A process for the preparation of vitamin K1 by the oxidation of an alkali metal salt of dihydrovitamin K1 with hydrogen peroxide in the presence of an iron (III) salt at a pH of 13.7 to 14.3. The dihydrovitamin K1 alkali metal salt is produced by the saponification of a dihydrovitamin K1 diester with sodium hydroxide or potassium hydroxide. Conveniently, the oxidation process follows the saponification of dihydrovitamin K1 without isolation of the product of the saponification reaction.
申请公布号 US5744624(A) 申请公布日期 1998.04.28
申请号 US19960764289 申请日期 1996.12.12
申请人 ROCHE VITAMINS INC. 发明人 DOERNER, MANFRED
分类号 B01J27/053;C07B61/00;C07C27/02;C07C37/64;C07C39/235;C07C46/00;C07C46/02;C07C51/377;C07C66/00;(IPC1-7):C07C50/14 主分类号 B01J27/053
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