摘要 |
A process for the preparation of vitamin K1 by the oxidation of an alkali metal salt of dihydrovitamin K1 with hydrogen peroxide in the presence of an iron (III) salt at a pH of 13.7 to 14.3. The dihydrovitamin K1 alkali metal salt is produced by the saponification of a dihydrovitamin K1 diester with sodium hydroxide or potassium hydroxide. Conveniently, the oxidation process follows the saponification of dihydrovitamin K1 without isolation of the product of the saponification reaction.
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