发明名称 Pyridazino quinoline compounds
摘要 PCT No. PCT/GB94/02295 Sec. 371 Date Apr. 17, 1996 Sec. 102(e) Date Apr. 17, 1996 PCT Filed Oct. 20, 1994 PCT Pub. No. WO95/11244 PCT Pub. Date Apr. 27, 1995The present invention relates to compounds, pharmaceutical compositions and methods of using compounds of formula (I) in the treatment and/or prevention of certain diseases or conditions. In formula (I), A is chosen from ortho substituted aryl or heteroaryl species, X is chosen from -OH, -SH, NHR and R1 or R2 is chosen from -(CH2)nL wherein L may be selected from a variety of substituents including aryl, heteroaryl and heterocyclic groups. The compounds are useful in treating and/or preventing neurological disorders associated with excitatory amino acids. <IMAGE> I
申请公布号 US5744471(A) 申请公布日期 1998.04.28
申请号 US19960637641 申请日期 1996.04.17
申请人 ZENECA LIMITED 发明人 BARE, THOMAS MICHAEL;DAVENPORT, TIMOTHY WAYNE;EMPFIELD, JAMES ROY;MCKINNEY, JEFFREY ALAN;SPARKS, RICHARD BRUCE
分类号 A61K31/50;A61K31/5025;A61P3/08;A61P3/10;A61P9/10;A61P25/00;A61P25/08;A61P25/28;A61P43/00;C07D215/56;C07D221/00;C07D221/04;C07D237/00;C07D471/04;C07D471/14;C07D495/14;(IPC1-7):A61K31/50;C07D491/14 主分类号 A61K31/50
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