| 发明名称 |
N-substituted glutamic acid derivatives with interleukin-1 beta converting enzyme inhibitory activity |
| 摘要 |
The present invention relates to N-substituted derivatives of glutamic acid of pharmaceutical interest, to pharmaceutical compositions which include compounds of the invention and pharmaceutically acceptable carriers, to methods of their preparation, and to their use in purification of interleukin-1 beta converting enzyme (ICE).
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| 申请公布号 |
US5744451(A) |
申请公布日期 |
1998.04.28 |
| 申请号 |
US19960700716 |
申请日期 |
1996.08.13 |
| 申请人 |
WARNER-LAMBERT COMPANY;BASF A.G. |
发明人 |
ALLEN, HAMISH JOHN;BANERJEE, SUBHASHIS;BRADY, KENNETH DALE;HODGES, JOHN COOKE;KOSTLAN, CATHERINE ROSE;TALANIAN, ROBERT VINCENT |
| 分类号 |
C07H5/04;A61K31/00;A61K31/04;A61K31/155;A61K31/435;A61K31/44;A61K31/4409;A61K31/4412;A61K31/4415;A61K31/506;A61K31/51;A61K31/675;A61K38/05;A61K38/06;A61K38/07;A61P3/00;A61P3/10;A61P9/10;A61P13/00;A61P13/12;A61P27/06;A61P43/00;C07D213/66;C07D417/06;C07K1/02;C07K5/06;C07K5/087;C07K14/00;G01N33/68;(IPC1-7):A61K38/05;A61K38/09 |
主分类号 |
C07H5/04 |
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