发明名称 Piperazino derivatives as neurokinin antagonists.
摘要 The invention relates to compounds of formula (I) wherein Z, Rc, y, m, u, Ar2, n, X, Rc', l and Ar2 are as described herein. These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.
申请公布号 ZA9709670(B) 申请公布日期 1998.04.28
申请号 ZA19970009670 申请日期 1997.10.28
申请人 SCHERING CORPORATION 发明人 DAVID J. BLYTHIN;XIAO CHEN;RICHARD J. FRIARY;KEVIN D. MCCORMICK;JOHN J. PIWINSKI;NENG-YANG SHIH;HO-JANE SHUE
分类号 A61K31/00;A61K31/445;A61K31/495;A61K31/496;A61P1/00;A61P11/00;A61P13/00;A61P13/10;A61P17/00;A61P25/04;A61P27/00;A61P27/02;A61P37/00;A61P43/00;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D409/14;C07D413/14;C07D417/14;C07D451/04;C07D451/06;C07D453/06;C07D471/08;C07D487/08 主分类号 A61K31/00
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