| 发明名称 |
TRANS-DICHLORO(BROMO)-BIS-[GAMMA-1,2,5-TRIMETHYL-4-(3,4-DIME- -THYL-3,4-DIHYDROXY-1-PENTINYL]-4-PIPERIDOL-ETHA SHOWING ANTHELMINTIC ACTIVITY |
| 摘要 |
FIELD: organic chemistry. SUBSTANCE: product: trans-dichloro(bromo)-bis-[gamma-1,2,5-trimethyl-4- -(3,4-dimethyl-3,4-dihydroxy-1-pentinyl] -4-piperidol-etha, NPt (II) of the formula [Pt(C<SB>15</SB>H<SB>27</SB>NO<SB>3</SB>)<SB>2</SB>Cl<SB>2</SB>]. Yield is 0.78 g (80%). Reagent 1: an aqueous solution of K<SB>2</SB>[PtCl<SB>4</SB>] or K<SB>2</SB>[PtBr<SB>4</SB>]. Reagent 1: gamma-1,2,5-trime- -thyl-4-(3,4-dimethyl-3,4-dihydroxy-1-pentinyl)-4-piperidol in alcohol. Reaction conditions: process is carried out at heating to 40 C for 24 h. Synthesized compound is used in medicine as an anthelmintic agent. EFFECT: improved method of synthesis. 1 tblm
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| 申请公布号 |
RU2109745(C1) |
申请公布日期 |
1998.04.27 |
| 申请号 |
SU19915002304 |
申请日期 |
1991.08.12 |
| 申请人 |
HIKISTAN;TADZHIKSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ VETERINARNYJ;TADZHIK NI SKIJ VETERINARNYJ;INST |
发明人 |
SICHINAVA LJUBOV' LEONOVNA;EVDOKIMOVA NINA PAVLOVNA;SANJUKOVICH GALINA SEMENOVNA;GLAZUNOVA ELENA MIKHAJLOVNA;IL'JASOV IRIK NURDAEVICH;SICHINAVA LJUBOV' LEONOVNA;EVDOKIMOVA NINA PAVLOVNA;SANJUKOVICH GALINA SEMENOVNA;GLAZUNOVA ELENA MIKHAJLOVNA;IL'JASOV IRIK NURDAEVICH |
| 分类号 |
C07F15/00;A61K31/295;A61K31/382;A61P33/10;(IPC1-7):C07F15/00 |
主分类号 |
C07F15/00 |
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