| 发明名称 |
PURINE AND GUANINE COMPOUNDS, PROCESS FOR PRODUCING THEM, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR PRODUCING PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
Compounds of formula I <IMAGE> where n=0-2; R1 is H, NH2 or a halogen; R2 is H or NH2; R3 is any of the four groups <IMAGE> (I) where m=0 or 1; and X is O, NR5, or S(O)0-2 and, in group (b), the X's may be the same or different. Compounds of the invention have utility as inhibitors of purine nucleoside phosphyorylase (PNP). |
| 申请公布号 |
HUT77436(A) |
申请公布日期 |
1998.04.28 |
| 申请号 |
HU19970001935 |
申请日期 |
1995.10.05 |
| 申请人 |
CHIROSCIENCE LIMITED |
发明人 |
BEASLEY,STEVEN COLLIN;HAUGHAN,ALAN FINDLAY;MONTANA,JOHN;WATSON,ROBERT JOHN |
| 分类号 |
A61K31/52;A61K31/522;A61P3/08;A61P17/00;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/00;A61P37/06;A61P37/08;C07D473/00;C07D473/18 |
主分类号 |
A61K31/52 |
| 代理机构 |
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