Technetium-99m labeled chelator incorporated cyclic peptides

摘要

The present invention describes novel radiopharmaceuticals of formula (I): (I) wherein J, K, L, and M, are amino acids or derivatives thereof and R', R1, R2 and n are as defined herein, that are radiolabeled cyclic compounds containing chelators which act as antagonists of the platelet glycoprotein IIb/IIIa complex, methods of using the same as imaging agents for the diagnosis of arterial and venous thrombi, and novel reagents for the preparation of the same and kits comprising the reagents.