HUMAN REG I-GAMMA PROTEIN

摘要

The present invention provides a polynucleotide (Reg I-gamma) which identifies and encodes a human Reg I-gamma. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding human Reg I-gamma. The invention also provides for the use of purified Reg I-gamma and its agonists in the production of recombinant proteins and in pharmaceutical compositions for the treatment of diseases associated with the expression of Reg I-gamma. Additionally, the invention provides for the use of Reg I-gamma antagonists and inhibitors, including antisense molecules to Reg I-gamma in pharmaceutical compositions for the treatment of diseases associated with the expression of Reg I-gamma. The invention also describes diagnostic assays which utilize the polynucleotide to hybridize with the transcripts and/or genomic DNA encoding Reg I-gamma and anti-human Reg I-gamma antibodies which specifically binds to Reg I-gamma.