ANTIMICROBIAL PEPTIDE ANALOGS OF GRAMICIDIN S AND COMPOSITIONS COMPRISING THEM
摘要
The invention concerns antimicrobial cyclic peptides and peptide analogs having relatively low hemolytic activity. Peptides of the invention are effective in killing and/or inhibiting growth of a number of microorganisms, including gram-positive bacteria, gram-negative bacteria, fungi and mycoplasma. Also disclosed are methods for inhibiting or killing such microorganisms, and therapeutic preparations for such inhibiting or killing.
申请公布号
WO9816549(A1)
申请公布日期
1998.04.23
申请号
WO1997US18693
申请日期
1997.10.10
申请人
PENCE, INC.;DEHLINGER, PETER, J.
发明人
KONDEJEWSKI, LESLIE, H.;HODGES, ROBERT, S.;WISHART, DAVID, S.;HANCOCK, ROBERT, E., W.;MCELHANEY, RONALD, N.;PRENNER, ELMAR, J.;LEWIS, RUTHVEN, N., A., H.