| 发明名称 |
SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1.BETA. CONVERTING ENZYME INHIBITORS |
| 摘要 |
The present invention relates to compounds that are inhibitors of interleukin1.beta. converting enzyme that have Formula (I, II or III). This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock, reperfusion injury, Alzheimer's disease, and shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1.beta. converting enzyme.
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| 申请公布号 |
CA2268103(A1) |
申请公布日期 |
1998.04.23 |
| 申请号 |
CA19972268103 |
申请日期 |
1997.10.09 |
| 申请人 |
BASF AKTIENGESELLSCHAFT;WARNER-LAMBERT COMPANY |
发明人 |
LUNNEY, ELIZABETH ANN;PLUMMER, MARK STEPHEN;SAWYER, TOMI;BRADY, KENNETH DALE;WALKER, NIGEL;HARTER, WILLIAM GLEN;SHAHRIPOUR, AURASH;ALLEN, HAMISH JOHN |
| 分类号 |
A61K31/192;A61K31/341;A61P1/00;A61P7/08;A61P19/02;A61P25/28;A61P31/04;C07C311/19;C07C311/29;C07C311/46;C07C323/67;C07D307/12;(IPC1-7):C07C311/29;A61K31/195;A61K31/34;C07C311/42 |
主分类号 |
A61K31/192 |
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