M protein analogue from Streptococcus pneumoniae

摘要

M Protein polypeptides and DNA (RNA) encoding such M Protein and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such M Protein for the treatment of infection. and bacterial infections. Antagonists against such M Protein and their use as a therapeutic to treat infection and bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of M Protein nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding M Protein and for detecting the polypeptide in a host.