METHOD AND DEVICE FOR ADMINISTERING DEXMEDETOMIDINE TRANSDERMALY

摘要

Transdermal administration of dexmedetomidine, the dextrorotatory isomer of mede tomidine, is described. The method involves sedating a patient by administering dexmedetomidine to a predetermined area of skin at an administration rate and for a time period effective to achieve the desired level of sedation. A therapeutic sy stem for transdermally administering the drug is also provided. The therapeutic system is in the form of a skin patch which is a laminated composite of a backing layer (10), an optional anchor adhesive layer (11), a contact adhesive layer (12), and one or m ore additional layers (13).