| 发明名称 |
A bioluminescent indicator for gene expression and detection of mutagensis based upon the expression of a gene for a modified green fluorescent protein |
| 摘要 |
A pre-coelenterazine peptide comprising a modified A. victoria GFP having an amino acid sequence in which Ser65 is replaced with Tyr. There is further provided a polynucleotide encoding the pre-coelenterazine peptide, allowing synthesis of large, pure amounts of coelenterazine.
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| 申请公布号 |
US5741668(A) |
申请公布日期 |
1998.04.21 |
| 申请号 |
US19950452295 |
申请日期 |
1995.05.26 |
| 申请人 |
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NY |
发明人 |
WARD, WILLIAM W.;CHALFIE, MARTIN |
| 分类号 |
C07D277/68;C07D487/04;C07K14/435;C12Q1/68;(IPC1-7):C12P21/00;C12N15/63;C07H21/04 |
主分类号 |
C07D277/68 |
| 代理机构 |
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