| 摘要 |
A cartridge holder (400) includes a holder body (420) having a cavity (421, 422) along a longitudinal axis of the holder body (420). A floating screw (440) has a longitudinal axis and a hole (441) through the length of the floating screw (440). The floating screw (440) is adapted to engage with the cavity (422) in such a way that the floating screw (440) is movable relative to the holder body (420) along the longitudinal axis of the holder body (420). But rotary movement of the floating screw (440) around the longitudinal axis of the holder body (420) is confined by a restriction (424) of the cavity (422). An outlet unit (430) having a stem (433) with a central hole (431) and a length greater than that of the floating screw (440) is adapted to be movably inserted into the hole (441) of the floating screw (440), so that a first end of the outlet unit (430) extends out of the hole (441) and a second end of the outlet unit (430) is engaged with the cavity (421). An end cap (410) is provided to engage with the cavity (421). In use a cartridge (450) is placed inside the cavity (421) of the holder body (420) between the end cap (410) and the outlet unit (430). The floating screw (440) can be screwed onto an endfitting (470) of a chromatography column (480) by turning the holder body (420) and, in the meantime, the outlet unit (430) is pushed toward the endfitting (470) so that a zero dead volume connection is achieved. Thus, the cartridge holder (400) fits to all brands of column endfittings by self-adjusting the relative position of floating screw (440) and outlet unit (430). The cartridge holder (400) also can be modified to connect a tubing (490) directly to endfitting (470) of chromatography column (480).
|
