The present invention provides polynucleotides which identify and encode a novel human nm23-like protein (H-nm23). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding H-nm23 and for a method for producing the protein. The invention also provides for the use of substantially purified H-nm23 for the treatment of diseases associated with the expression of H-nm23. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotides which hybridize with naturally occurring sequences encoding H-nm23 and antibodies which specifically bind to the protein.
申请公布号
WO9811232(A3)
申请公布日期
1998.04.16
申请号
WO1997US16173
申请日期
1997.09.12
申请人
INCYTE PHARMACEUTICALS, INC.;BANDMAN, OLGA;HAWKINS, PHILLIP, R.