METHOD AND APPARATUS FOR ASSAY ANALYSIS

摘要

The present invention provides a detection system comprising means (12) for supporting a multiple sample assay (11) in an inspection station, plural addressable photosensitive detector elements in an array (20) which is positioned relative to the inspection station, means (30, 32) for addressing the groups of elements at regularly occurring intervals of time so as to generate linked numerical values for analysis, means (44, 46) for computing the arithmetic mean of the linked numerical values read out, and means for supplying as output information the numerical value of the computed arithmetic mean of the linked values. A method of analysing a multiple sample assay is also provided. In order to enable corrections for the effects of chemical or colour quench, the system can be calibrated by performing a large number of exposures of at least part of the array to a sample of known, constant activity and having a known amount or concentration of quenching agent, and repeating this process for each of a number of other samples with differing amounts or concentrations of said agent. The photosensor outputs obtained in the course of these processes are statistically analysed to provide an index from which look-up tables for colour and/or chemical quench correction can be compiled.