QUINUCLIDINE DERIVATIVES AS ANTAGONISTS OF MUSCARINIC RECEPTORS

摘要

The invention concerns compounds of formula (I) in which: R1 represents one hydrogen atom, one halogen such as fluorine, chlorine, bromine or iodine, one C1-6 alkyl group, linear or branched, one C1-2 perfluoroalkyl group or one nitro group, and R2 and R3 represent, independently of each other, one hydrogen atom, one halogen such as fluorine, chlorine, bromine or iodine, one C1-6 alkyl group, linear or branched, or a C1-6 alkoxy group, in the form of enantiomers, of diastereoisomers, or mixtures of these different forms, including racemic mixtures as well as their N-oxide derivative, their methiodide or their additive salts to pharmaceutically acceptable acids. The invention is applicable in therapeutics.