发明名称 |
Diterpenes and flavonoids as 5-alpha-reductase inhibitors |
摘要 |
Strong 5 alpha -reductase inhibitors are extracted and fractionated from Thuja orientalisis and other similar crude drugs or they may be purified as diterpenes in isolated form. The inhibitors are used either on their own or as active ingredients of therapeutics in the treatment of diseases caused by the overactivity of 5 alpha -reductase or the hypersecretion of androgens, such as male pattern baldness, androgenetic alopecia, hirsutism, acne, prostatomegaly and cancer of the prostate. |
申请公布号 |
EP0747048(A3) |
申请公布日期 |
1998.04.15 |
申请号 |
EP19960109269 |
申请日期 |
1996.06.10 |
申请人 |
KABUSHIKI KAISHA YAKURIGAKU CHUO KENKYUSHO |
发明人 |
TAKAHASHI, HIDEHIKO;HARA, SUSUMU;MATSUI, RIEKO |
分类号 |
A61K8/49;A61K8/97;A61K31/015;A61K31/045;A61K31/047;A61K31/19;A61K36/00;A61K36/13;A61Q5/00;A61Q7/00;A61Q7/02;A61Q19/00 |
主分类号 |
A61K8/49 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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