发明名称 |
Enzymatic synthesis of 2',5'-oligoadenylate-2',3'-cyclophosphates and treatment of papillomaviruses |
摘要 |
PCT No. PCT/EP93/02596 Sec. 371 Date Nov. 21, 1996 Sec. 102(e) Date Nov. 21, 1996 PCT Filed Sep. 24, 1993 PCT Pub. No. WO95/08555 PCT Pub. Date Mar. 30, 1995An enzymatic synthesis is disclosed for papillomavirus inhibitors which are 2',5'-oligoadenylate-2',3'-cyclophosphates having the formula <IMAGE> I in which 0</=n</=10, in particular from >/=0 to 10, preferably 1 or 2. Pharmaceuticals which contain these compounds as the active ingredient, and their use to treat diseases caused by papillomaviruses are also discussed.
|
申请公布号 |
US5739013(A) |
申请公布日期 |
1998.04.14 |
申请号 |
US19960615246 |
申请日期 |
1996.11.21 |
申请人 |
BUDOWSKY, EDWARD I.;GAVRILOV, ALEXANDER E.;PIVASYAN, ARMAN D. |
发明人 |
BUDOWSKY, EDWARD I.;GAVRILOV, ALEXANDER E.;PIVASYAN, ARMAN D. |
分类号 |
A61K31/70;A61K31/7088;A61P17/00;A61P31/12;A61P35/00;C07H21/00;C12P19/34;(IPC1-7):C12P19/34;C12N9/22;A01N43/04;C07H21/04 |
主分类号 |
A61K31/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|