| 摘要 |
PCT No. PCT/DE94/01395 Sec. 371 Date May 31, 1996 Sec. 102(e) Date May 31, 1996 PCT Filed Nov. 24, 1994 PCT Pub. No. WO95/15161 PCT Pub. Date Jun. 8, 1995The use of oxirane carboxylic acids having the formula I: <IMAGE> (I) in which R1 and R2 are independently selected from hydrogen, halogen, straight-chain or branched 1-4C alkyl groups, straight-chain or branched 1-4C alkoxy groups, nitro or trifluoromethyl; R3 is hydrogen or straight-chain or branched 1-4C alkyl; Y is -O-(CH2)m-, where m is zero or a whole number from 1 to 4, and n is a whole number from 2 to 8, or a pharmaceutically acceptable salt thereof, is disclosed for treating heart insufficiency.
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