发明名称 Enantiomerically pure hydroxylated xanthine compounds to treat autoimmune diabetes
摘要 There is disclosed compounds and pharmaceutical compositions that are a resolved R or S (preferably R) enantiomer of an omega -1 alcohol of a straight chain alkyl (C5-8) substituted at the 1-position of 3,7-disubstituted xanthine. The inventive compounds are effective in modulating cellular response to external or in situ primary stimuli, as well as to specific modes of administration of such compounds in effective amounts.
申请公布号 US5739138(A) 申请公布日期 1998.04.14
申请号 US19950457703 申请日期 1995.06.01
申请人 CELL THERAPEUTICS, INC. 发明人 BIANCO, JAMES A.;WOODSON, PAUL;PORUBEK, DAVID;SINGER, JACK
分类号 C07D473/06;A61K;A61K31/44;A61K31/519;A61K31/52;A61K31/522;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P3/10;A61P5/14;A61P7/00;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P15/06;A61P17/06;A61P17/14;A61P19/02;A61P19/10;A61P25/20;A61P29/00;A61P31/04;A61P35/00;A61P35/02;A61P35/04;A61P37/06;A61P39/02;A61P43/00;C07D473/04;C07D473/10;(IPC1-7):A61K31/52 主分类号 C07D473/06
代理机构 代理人
主权项
地址