发明名称 Heterodimer peptides with immunomodulatory effect
摘要 A peptide heterodimer of two non-identical peptide monomers wherein the first monomer is of formula (I): A-R1-R2-Cys-(-R3-)-xB wherein each A is independently selected from H, a protecting group or at least one amino acid residue independently selected from the group of amino acid residues having aliphatic side chains, aliphatic hydroxyl side chains, basic side chains, acidic side chains, secondary amino groups, amide side chains, aromatic side chains, and sulphur containing side chains; R1 is a residue of an amino acid selected from serine (Ser), glycine (Gly), alanine (Ala) and aspartic acid (Asp), R2 is a residue of an amino acid selected from proline (Pro), pipecolic acid (Pec), and isoleucine (Ile), R3 is a residue of an amino acid selected from phenylalanine (Phe), isoleucine (Ile), proline (Pro) and alanine (Ala), x is 0 or 1.
申请公布号 AU4406097(A) 申请公布日期 1998.04.14
申请号 AU19970044060 申请日期 1997.09.15
申请人 ASTRA AKTIEBOLAG (PUBL) 发明人 HIKAN BERGSTRAND;TOMAS ERIKSSON;MAGNUS LINDVALL;BENGT SARNSTRAND
分类号 A61K38/00;C07K5/103;C07K7/06 主分类号 A61K38/00
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