| 摘要 |
Use of a compound comprising one or more alpha -amino acid residues of general formula (I), wherein R is selected from the group consisting of hydrogen, optionally substituted C1-C20 alkyl, C1-C20 alkenyl, aryl and aralkyl groups and a group R<5>-OCO- where R<5> is selected from C1-C20, C1-C20 alkenyl, aryl and aralkyl groups; R<1> and R<2> are independently selected from the group consisting of hydrogen and optionally substituted C1-C6 alkyl, C1-C6 alkenyl, C7-C12 arylalkyl and aryl groups; or R<1> and R<2> together represent a group =CR<6>R<7>, wherein R<6> and R<7> are independently selected from hydrogen, halogen, and optionally substituted C1-C6 alkyl and aryl groups; wherein the compound does not contain free thiol groups; or a pharmaceutically acceptable salt thereof in the preparation of a medicament suitable for the treatment of a disease state caused by production of free radical species or in which free radical species are produced is provided, together with formulations and methods for their preparation. |
