| 摘要 |
<p>A method of analyzing one or more samples of a body fluid such as whole blood from a patient by determining whether or not there is a significant difference or change in the comparative determinants of viscosity in the body fluid sample, the comparative determinants being derived using a probe which provides increased sensitivity and correspondingly improved relative viscosity values when used together with a suitable measuring device such as a SONOCLOT® Analyzer, in order to identify the presence or incipiency of a symptomatic or asymptomatic pathology caused by or leading to said differences or changes in viscosity, comprising: (1) placing a first aliquot of the body fluid sample in a suitable container to be used as a control aliquot; (2) placing a second aliquot in a suitable container to be used as an active aliquot; (3) measuring relative viscosity of the control and active aliquots and obtaining data which are comparative determinants of viscosity by using said probe which comprises in particular a hollow tube of glass, ceramic, plastic or metal, the end thereof which enters the aliquot to be measured, having been sealed with bone wax or dental wax; and (4) identifying the presence or incipiency of said symptomatic or asymptomatic pathology caused by or leading to said differences or changes in viscosity, by analysis of the comparative determinants of viscosity obtained as recited above for the control and active aliquots, wherein the values for the control and active aliquots are obtained (i) at different times from the mammal, (ii) under conditions of significantly changed homeostasis of the mammal, (iii) in the absence and/or presence of, respectively, a viscometric modulator, or (iv) from the same mammal in a healthy state, free of the pathology, and from the mammal being tested, respectively, or any combination of the above testing circumstances.</p> |
