发明名称 |
1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE HETEROCYCLIC ANALOGUES HAVING ANTAGONISTIC ACTIVITY ON ADENOSINE A2a RECEPTOR |
摘要 |
The compounds of general formula (I), wherein A is a pyrazole, imidazole or triazole ring, R is formula (II), wherein R1 and R2, which are the same or different, are H, OH, halogen, C1-4 alkoxy, C1-4 alkyl, nitro, amino, cyano, C1-4 haloalkyl, C1-4 haloalkoxy, carboxy, carboxamido groups; moreover the OH group, together with one of R1 or R2, or R1 and R2, can form the methylenedioxy group -O-CH2-O-; n is an integer from 0 to 4, are useful as therapeutical agents.
|
申请公布号 |
WO9705138(A1) |
申请公布日期 |
1997.02.13 |
申请号 |
WO1996EP02881 |
申请日期 |
1996.07.02 |
申请人 |
SCHERING-PLOUGH S.P.A.;BARALDI, PIER, GIOVANNI;CACCIARI, BARBARA;VIZIANO, MONICA;DIONISOTTI, SILVIO;ONGINI, ENNIO |
发明人 |
BARALDI, PIER, GIOVANNI;CACCIARI, BARBARA;VIZIANO, MONICA;DIONISOTTI, SILVIO;ONGINI, ENNIO |
分类号 |
C07D487/14;(IPC1-7):C07D487/14;A61K31/495 |
主分类号 |
C07D487/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|