发明名称 |
Thermostable nucleic acid polymerase from Thermococcus gorgonarius |
摘要 |
A purified thermostable enzyme is derived form the thermophilic archaebacterium Thermococcus gorgonarius. The enzyme can be native or recombinant, retains approximately 90 % of its activity after incubation for two hours at 95 DEG C in the presence of stabilizing agents and possesses 3'-5' proofreading exonuclease activity. Thermostable DNA polymerases are useful in many recombinant DNA techniques, especially nucleic acid amplification by the polymerase chain reaction (PCR).
|
申请公布号 |
EP0834570(A1) |
申请公布日期 |
1998.04.08 |
申请号 |
EP19960115874 |
申请日期 |
1996.10.03 |
申请人 |
ROCHE DIAGNOSTICS GMBH |
发明人 |
BONCH-OSMOLOVSKAYA, ELIZAVETA DR.;SVETLICHNY, VITALY DR.;ANKENBAUER, WALTRAUD, DR.;SCHMITZ-AGHEGUIAN, GUDRUN DR.;ANGERER, BERNHARD DR.;EBENBICHLER, CHRISTINE;LAUE, FRANK |
分类号 |
C12N15/54;C12N1/21;C12N9/12;C12Q1/68;(IPC1-7):C12N15/52;C12N15/70;C12P21/00 |
主分类号 |
C12N15/54 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|