发明名称 NEUROPROTECTIVE 3,4-DIHYDRO-2(1H)-QUINOLONE COMPOUNDS
摘要 The present invention is directed to compounds of formula (I), and the pharmaceutically acceptable acid addition salts thereof, wherein R is selectetd from the group consisting of F, -CF3, -OCH3, -O(C1)alkyl substituted with 1 to 3 fluoro atoms, -O(C2)alkyl substituted with 1 to 5 fluoro atoms, and -O(C3)alkyl substituted with 1 to 7 fluoro atoms. The compounds of formula (I) are useful in the treatment of stroke, traumatic brain injury and central nervous system degenerative diseases.
申请公布号 CA2146260(C) 申请公布日期 1998.04.07
申请号 CA19932146260 申请日期 1993.07.23
申请人 PFIZER INC. 发明人 CHENARD, BERTRAND L.
分类号 A61K31/47;A61P25/00;C07D401/06;(IPC1-7):C07D401/06 主分类号 A61K31/47
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