| 发明名称 |
Tissue plasminogen activator variants |
| 摘要 |
PCT No. PCT/US92/10677 Sec. 371 Date Aug. 17, 1994 Sec. 102(e) Date Aug. 17, 1994 PCT Filed Dec. 14, 1992 PCT Pub. No. WO93/12225 PCT Pub. Date Jun. 24, 1994Biologically active variant tissue plasminogen activators are disclosed. The disclosure focuses on position 276 variants that exhibit enhanced fibrin specificity.
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| 申请公布号 |
US5736134(A) |
申请公布日期 |
1998.04.07 |
| 申请号 |
US19940244773 |
申请日期 |
1994.08.17 |
| 申请人 |
GENENTECH, IN.C |
发明人 |
HEYNEKER, HERBERT L.;VEHAR, GORDON A.;PAONI, NICHOLAS F.;BENNETT, WILLIAM F. |
| 分类号 |
A61K38/00;C12N1/21;C12N9/72;C12N15/10;C12N15/67;C12N15/71;(IPC1-7):A61K38/48;C12N9/48;C07H21/04 |
主分类号 |
A61K38/00 |
| 代理机构 |
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| 主权项 |
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