发明名称 |
Non-hemolytic mosquitocidal microorganisms |
摘要 |
The cytA gene encoding the 28 kDa polypeptide of Bacillus thuringiensis israelensis crystals was disrupted in the 72 MDa resident plasmid by in vivo recombination. The absence of the 28 kDa protein in B. thuringiensis israelensis did not affect the crystallization of the other toxic components of the parasporal body. However, the absence of the 28 kDa protein did abolish the hemolytic activity of B. thuringiensis serovar israelensis crystals. The mosquitocidal activity of the 28 kDa protein-free crystals did not differ significantly from the wild-type crystals.
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申请公布号 |
US5736513(A) |
申请公布日期 |
1998.04.07 |
申请号 |
US19930149950 |
申请日期 |
1993.11.10 |
申请人 |
INSTITUT PASTEUR |
发明人 |
DELECLUSE, ARMELLE;KLIER, ANDRE;RAPOPORT, GEORGES |
分类号 |
A01N63/02;C07K14/325;C12N1/21;C12N15/32;(IPC1-7):A01N63/02 |
主分类号 |
A01N63/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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