Method of testing inert, displaceable diluents used in forming shaped hydrogel articles

摘要

Method of testing inert displaceable diluents used in forming shaped hydrogel articles such as soft contact lenses prepared by the steps of: (1) molding or casting a polymerization mixture including: (a) a monomer mixture having a major proportion of one or more hydrophilic monomers such as 2-hydroxyethyl methacrylate, and one or more cross-linking monomers; and (b) an inert, displaceable diluent chosen from: (i) ethoxylated alkyl glucoside; (ii) ethoxylated bisphenol A; (iii) polyethylene glycol; (iv) mixture of propoxylated and ethoxylated alkyl glucoside; (v) single phase mixture of ethoxylated or propoxylated alkyl gtucoside and C2-12 dihydric alcohol; (vi) adduct of epsilon -caprolactone and C2-6alkanediols and triols; (vii) ethoxylated C3-6alkanetriol; and (viii) mixtures of one or more of (i) through (vii), under conditions to polymerize the monomer mixture to produce a shaped gel of a copolymer of the monomers and the diluent; and (2) thereafter replacing the diluent with water.