发明名称 |
Peptide-enhanced cationic lipid transfections |
摘要 |
The present invention discloses compositions useful for transfecting eukaryotic cells comprising nucleic acid complexes with peptides, proteins or protein fragments, wherein the peptide is optionally covalently coupled to a DNA-binding group, and cationic lipids useful for transfecting eukaryotic cells. Methods for the preparation of transfecting compositions and use as intracellular delivery agents and extracellular targeting agents are also disclosed.
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申请公布号 |
US5736392(A) |
申请公布日期 |
1998.04.07 |
申请号 |
US19960658130 |
申请日期 |
1996.06.04 |
申请人 |
LIFE TECHNOLOGIES, INC. |
发明人 |
HAWLEY-NELSON, PAMELA;LAN, JIANQING;SHIH, POJEN;JESSEE, JOEL A.;SCHIFFERLI, KEVIN P. |
分类号 |
C12N15/09;A61K9/127;A61K31/70;A61K35/76;A61K48/00;C12N7/04;C12N15/88;(IPC1-7):C12N15/00;C07K14/005;G01N33/92 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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