| 摘要 |
An improved sample well is provided for carrying out a biological or chemical pr ocess, such as a nucleic acid assay or an immunoassay, on a liquid sample. The sample well i ncludes a cap with a restricted aperture sufficient in size to receive the distal end of a disposable pipette tip. The pipette tip is initially inserted into the aperture to introduce a liquid sample into th e sample well, and is allowed to remain within the aperture while the sample reacts with a reagent con tained within the sample well. In this way, the pipette tip effectively closes off the sample well while the reaction is taking place, thereby reducing evaporative loss of the sample and avoiding cross -contamination with samples contained in adjacent sample wells. The sample wells may also be constru cted of, or include therein, different materials which perform different functions in the biological or chemical process, thereby permitting assembly of different groups of sample wells for different as say formats. |
