HEX II TUMOR-SPECIFIC PROMOTER AND USES THEREOF IN CANCER THERAPY

摘要

The present invention relates to a tumor-specific promoter for use in gene targeted therapy that is differentially regulated in cancer cells, which comprises Hex II promoter. The present invention also relates to a gene construct, which include Hex II promoter in a vector selected from pCAT basic expression vector p DELTA ElsplB and a shuttle plasmid, and which optionally includes beta -gal or HSV Tk.