发明名称 |
PHARMACEUTICAL COMPOSITION FOR THE INHIBITION OF ANGIOGENESIS |
摘要 |
Fumagillin and its salts have an angiogenesis inhibiting activity and are useful for prophylaxis and treatment of diseases induced by abnormally stimulated neovascularization. The invention also provides certain pharmaceutical compositions comprising fumagillin or its salt, and an agent which potentiates angiogenesis inhibition such as heparin and sulfated cyclodextrins such as beta-cyclodextrin tetradecasulfate. |
申请公布号 |
KR0128287(B1) |
申请公布日期 |
1998.04.02 |
申请号 |
KR19890000441 |
申请日期 |
1989.01.17 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES LTD.;CHILDERN HOSPITAL |
发明人 |
JUDAH FOLKMAN;DONALLD, LNGBER;TAKESHI, FUJITA;TSUNEO, KANAMARU |
分类号 |
C07D303/16;A61K31/335;A61K31/336;A61K31/395;A61K31/57;A61K38/18;A61K47/48;A61L27/36;A61L27/54;A61P9/00;C07D303/24;C07K14/50;C08B37/16;(IPC1-7):A61K31/335 |
主分类号 |
C07D303/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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