发明名称 |
NEW PHARMACEUTICALLY ACTIVE COMPOUNDS |
摘要 |
The present invention provides optionally substituted and/or annulated compounds of formula (I) wherein X, Y, Z and A is each independently carbon or nitrogen, and at least two of X, Y, Z and A are carbon; and pharmaceutically acceptable salts thereof with the proviso that: 3-(1H-Indol-3-yl)-1H-quinoxalin-2-one, 3-(2-Methyl-1H-indol-3-yl)-1H-quinoxalin-2-one, and 3-(1,2-Diphenyl-1H-indol-3-yl)-1H-quinoxalin-2-one are excluded from compounds of formula (I). The invention includes the use of compounds of formula (I) in medical therapy, particularly in the therapy of conditions requiring inhibition of protein kinase C.
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申请公布号 |
WO9813368(A1) |
申请公布日期 |
1998.04.02 |
申请号 |
WO1997SE01582 |
申请日期 |
1997.09.19 |
申请人 |
ASTRA AKTIEBOLAG (PUBL);BERGSTRAND, HAAKAN;KARABELAS, KOSTAS;SJOE, PETER |
发明人 |
BERGSTRAND, HAAKAN;KARABELAS, KOSTAS;SJOE, PETER |
分类号 |
C07D403/04;C07D405/14;C07D471/04;C07D475/00;C07D475/02;C07H19/04;(IPC1-7):C07D471/04;A61K31/50 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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