Transdermal administration of steroid hormones using diethanolamides of C12-C18 fatty acids as permeation enhancers.

摘要

Matrix-type transdermal patches for administering steroids comprising a matrix of one or more steroid hormones, a pressure sensitive adhesive and a diethanolamide of a C12-C18 fatty acid as a permeation enhancer. These diethanolamides provide unexpectedly superior permeation enhancement as compared to related known enhancers in such patches.